
Mitochondria form a dynamic network constantly undergoing morphological changes through fission, fusion and transport. The balance of these dynamic processes not only determines mitochondrial network morphology, but also integrity. Our lab focus on characterizing the regulatroy pathways of mitochondria dynamics for better understanding the pathogenesis of diseases derived from mitochondria dysfunctions.
GOAL
Clarifying the roles of mitochondria in tumorigenesis, senescence and metabolic disorders.
AIM
Characterizing the regulatory pathways of mitochondrial activity and dynamics.
APPROACH
Elucidating mitochondrial and cellular responses under different stress conditions in yeast and mammalian cells.
APPLICATIONS
Clarifying the roles of mitochondria in tumorigenesis, senescence and metabolic disorders.
AIM
Characterizing the regulatory pathways of mitochondrial activity and dynamics.
APPROACH
Elucidating mitochondrial and cellular responses under different stress conditions in yeast and mammalian cells.
APPLICATIONS
- Developing novel therapeutic strategies for diseases derived from mitochondria dysfunctions.
- Establisiing a platform to clarify underlying mechanisms of drugs targeted to mitochondria.